Summer Project 2018
Synthesis, characterization and applications of Ruthenium ter-pyridine based photosynsitizers
In this project, I synthesized Ruthenium ter-pyridine based photosynsitizers and characterized them using 1H-NMR, UV-vis spectroscopy, Fluorescence spectroscopy. Later on, I tested their application in Hydrogen evolution using Co catalyst and HBF4 as the proton source.
Summer Project 2017
Interactions and structure of various liposomes on adsorbed PEO polymer layer
This project expands the study of liposomes adsorption on charged polymers to the case of neutral PEO polymer layer on mica surface. This is to mimic the adsorption of liposomes to a soft surface, in this case, neutral polymer layers under aqueous environment. In this project I prepared and examined the adsorption and structure of small unilamellar vesicles (SUVs), so called liposomes, of various phospholipids (HSPC, DMPC and DPPC) that were prepared according to the standard procedure. The adsorption of the PC liposomes onto mica-PEO polymer layer and its complexes structure were determined by using atomic force microscopy (AFM). The findings on the ability of liposomes to adsorb on the PEO surface and its morphology is necessary to further study the efficiency of such complexes in reducing friction.
Summer Project 2016
Synthesis and Characterization of Amide Based Ligands Containing Appended Phosphine group and Their Metal Complexes.
The research work includes the synthesis and characterizations of pyridine-amide based ligands containing diphenylphosphine groups. It also discusses about the formation of Cobalt complex (i.e., metallogand) having diphenylphophines as appended groups which can further lead to heterometallic coordination complexes to Metal Organic Frameworks (MOFs) to facilitate precise control over the placement of molecular components with potential applications in catalysis, magnetism, gas and vapor sorption, separation and luminiscence.
Summer Project 2015
Synthesis and Characterization of a Nitrogen Mustard derived from 2,2-(phenylazanediyl)diethanol.
I was able to successfully synthesize 4-(bis(2-chloroethyl)amino)benzaldehyde and carry out synthesis of N,N-bis(4-(bis(2-chloroethyl)amino)benzylidene)benzene-1,2-diamine , a nitrogen mustard. Thereafter, I characterized the synthesized molecules using various analytical techniques like NMR spectroscopy, ESI-Mass spectroscopy, FT-IR spectroscopy.
The compounds that I synthesized one is commercially available but the laboratory synthesis could be done at a much lower cost which could be very useful. In addition the project reflected that the precursor used in the synthesis of 4-(bis(2-chloroethyl)amino)benzaldehyde may be modified with other functionalities for further conjugation.