Sourav Acharya

Senior Research Fellow

Department of Chemical Sciences, IISER Kolkata

CV and Publications

About me

I am currently a 4th year doctoral research scholar in the Department of Chemical Sciences under the supervision of Prof. Arindam Mukherjee at Indian Institute of Science Education and Research Kolkata. My research focuses on Chemical biology, Molecular chemistry of transition metal complexes and their applications in anti-cancer activities. I got interested in this field of research after he carried out my 1st summer internship (2014) with Dr. Chittaranjan Sinha at Jadavpur University.

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Computational skills

Microsoft Office (MS Word, Powerpoint, Excel), ChemDraw for chemical structure analysis, JeoL Delta NMR, MestRenova, TopSpin,Cris Alis Pro for XRD, Mercury, Origin, GraphPad prism; Schrodinger and Gold for docking, Lassex for Confocal Microscopy, Flojo for FACS study.

Instrumental skills

Jeol ECS 400 MHz and Bruker Advance III 500MHz NMR,FT-IR , UV-Vis(Carry 300/Perkin Elmer), Micro plate Reader,Bio Safety Cabinet (Lavel 2),BD FACSARIA III & FACSCalibur, Confocal Laser Scanning Microscope Leica TCS SP8, Olympus CKX41 Inverted microscope.

Laboratory skills

Synthesis of metal based (Ru and Pt) anticancer agents purify by column chromatography, HPLC, crystallization. Human cancer cell culture and effect of drugs on their toxicity by in vitro studies.

Successful people do what unsuccessful people are not willing to do. Don't wish it were easier; wish you were better.

Jim Rohn

Research Interest

Devolopment of metal based anti cancer agents and phosphoramide mustard derivaties

My research focus on the development of new Ru and Pt based metal complexes with different bioactive ligands having different in vitro mechanism of action to kill the cancer cells.I alsowork on the development f different fluorescence Phosphoramidate mustard derivaties with theranostic property.

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Recent Publications

Dalton Trans 2019

Amrita Sarkar, Sourav Acharya, Kumar Khushvant, Kallol Purkait and Arindam Mukherjee (Dalton Trans 2019 , 48, 7187-7197, DOI: 10.1039/C8DT04687E); Cytotoxic Ru(II)-p-cymene complexes of an anthraimidazoledione: halide dependent solution stability, reactivity and resistance to hypoxia deactivation. Equal contribution.

Polyhedron 2019(Invited Contribution)

Sudipta Bhattacharyyaa , Sourav Acharya, Suman Kr. Dey, Kavya Vipparthi, Sandeep Singh and Arindam Mukherjee. Fluorescent cyclic phosphoramide mustards and their cytotoxicity against cancer and cancer stem cells. Invited contribution on the special issue of Prof. Akhil Ranjan Chakraborty 65th Birthday, in Polyhedron, 2019. Just Accepted.

Inorganic Chemistry 2019

Sourav Acharya, Moumita Maji, Ruturaj, Kallol Purkait, Arnab Gupta and Arindam Mukherjee*. Inorganic Chemistry 2019.Synthesis, Structure,Stability and Inhibition of Tubulin Polymerization by RuII-p-cymene Complexes of Trimethoxyaniline Based Schiff Bases.Just Accepted.

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