“In the right light, at the right time, everything is extraordinary.”
- Aaron Rose.
Recent years have seen a propensity towards sustainability with the ultimate target of developing greener and environmentally friendly catalytic pathways. One of the emerging fields involves visible light photocatalysis which bypasses the employment of harsher thermal and UV-irradiation for realization of targeted reactions. To escape the flatland and enter into the realm of three-dimensionality, an important feature of pharmaceutically and commercially salient molecules, Dearomative Cycloadditions have emerged as a potential working platform. As seen in the recent modish works from several renowned groups worldwide, the inclusion of heterocyclic systems in dearomatization-based protocols has been more prominent.
My current research focuses on studying the properties and reactivities of aromatic hydrocarbon-based substrates towards Dearomative Cycloaddition reactions. This takes into account the detailed exploration of the photophysical properties of the palette of photosensitizers available at hand and correlates those towards synthesizing polycyclic three-dimensional motifs bearing one/more stereocentres with potential application in pharmaceutical or agrochemical purposes. This field has high potential owing to the large abundance of the two-dimensional, aromatic precursors available to be treated as suitable substrates to transform into intricate architecture bearing motifs in high regio- and diastereoselective fashions.
